Oral Melanotic Macule: Symptoms and Treatment Skinsight Brown spots, especially on the lips, can be alarming to some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non cancerous labial melanotic macule. Does Melanotic Macule Go Away TikTok What Caused These Multiple Hyperpigmented Macules of the Mouth? Oral pigmentation in children: a diagnostic challenge Archives of Disease in Childhood Oral Malignant Melanoma Oral Cancer Foundation Information and Resources about Oral Head and Neck Cancer